Table 2.
Results EORTC QLQ-C15-PAL for All Responders (n = 121)
| Domains | Inclusion | Month 1 | Month 2 | Month 3 | Month 6 | Month 9 | Month 12 |
|---|---|---|---|---|---|---|---|
| Patients alive | 155 | 154 | 151 | 146 | 123 | 98 | 81 |
| PROM response rate | 121 (78%) | 103 (67%) | 94 (62%) | 78 (53%) | 63 (51%) | 44 (45%) | 35 (43%) |
| Mean (SD) | |||||||
|---|---|---|---|---|---|---|---|
| Overall QoL | 61.8 (24.6) | 63.8 (22.9) | 62.3 (24.3) | 62.2 (23.4) | 62.4 (22.0) | 68.3 (18.6) | 69.0 (18.6) |
| Physical function | 75.4 (24.6) | 76.1 (23.5) | 78.7 (20.8) | 79.1 (22.6) | 79.0 (22.9) | 82.3 (23.0) | 84.0 (15.1) |
| Emotional function | 79.9 (24.3) | 81.7 (22.9) | 81.7 (22.4) | 82.5 (19.9) | 83.6 (18.6) | 84.5 (20.8) | 86.6 (17.3) |
| Fatigue | 36.6 (26.0) | 38.6 (22.6) | 40.7 (24.6) | 38.0 (25.2) | 37.3 (23.9) | 30.7 (29.4) | 27.8 (22.9) |
| Nausea/vomiting | 11.6 (24.2) | 10.9 (20.6) | 13.3 (21.5) | 15.0 (26.7) | 11.8 (21.0) | 8.3 (17.8) | 6.5 (13.4) |
| Pain | 21.8 (25.3) | 21.8 (26.0) | 23.7 (27.5) | 20.7 (24.8) | 19.0 (24.5) | 15.5 (21.7) | 14.4 (19.2) |
| Dyspnea | 19.0 (27.6) | 23.6 (28.3) | 21.5 (26.3) | 22.2 (26.1) | 19.6 (21.3) | 18.6 (19.7) | 19.4 (23.1) |
| Sleep disturbance | 36.1 (33.4) | 25.4 (27.9) | 25.8 (30.3) | 27.3 (31.9) | 23.8 (24.3) | 29.5 (28.9) | 23.1 (28.5) |
| Appetite loss | 17.8 (31.4) | 16.5 (25.2) | 18.3 (26.2) | 22.1 (29.9) | 19.0 (30.9) | 12.1 (25.0) | 11.1 (19.5) |
| Constipation | 15.4 (25.8) | 17.2 (24.3) | 18.6 (24.8) | 15.0 (20.6) | 17.5 (23.8) | 15.9 (23.3) | 17.6 (27.0) |
Overall QoL scores shown in bold values.