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. 2025 Jul 31;12:1598991. doi: 10.3389/fnut.2025.1598991

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Copyright © 2025 Dai, Li, Li and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Diagram showing two panels of biological pathway analysis. Panel A presents pathways like CGMP-PKG and MAPK with varying protein ratios and significance, indicated by bubble size and color. Panel B features reactome processes such as membrane trafficking and fatty acid metabolism, with protein percentages represented by red and blue bars indicating significance levels. — ATF-2 was indicated to be the potential target of α-GML in up-regulation of TJ expression based proteomic analysis. (A) KEGG analysis on the common targets. (B) Signal pathway enrichment by Reactome analysis.