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. 2025 Jul 25;17(7):5710–5717. doi: 10.62347/FFUV4293

Table 1.

Literature regarding synchronous GC and HCC

Study Case Age Gender Diagnosis Medical history Pathology Therapy Complications Outcome
Kim YI et al (1989) [6] 1 66 Female GC+HCC Hepatitis B P/D AC; HCC B-I gastrectomy + left lobectomy Bile bleak HCC recurrence after 10 mos postoperatively
Uenishi T et al (2003) [5] 13 48-76 Male GC+HCC Chronic hepatic disease 5 P/D, 4 M/D and 4 W/D AC; HCC STG/TG/WR + right lobectomy/Segmentectomy/limited resection 1 died of hepatic failure, 4 massive ascites, 1 liver abscess and 1 intra-abdominal bleeding 6 died during 7 mos to 49 mos, 3 HCC recurrence, 3 alive at the end of the study
Chang JY et al (2003) [7] 1 74 Male GC+HCC+CC No chronic illness W/D AC; W/D HCC; M/D CC STG + left lobectomy + Right hepatic WR Uneventful Under follow-up
Ewertsen C et al (2009) [8] 1 71 Male GNEC+HCC Type 2 diabetes; chronic heart failure; chronic obstructive lung disease; adiposities P/D NEC; HCC Local resection for GNEC + sorafenib for HCC Uneventful Normal in the follow-up after 6 mos
Ramakrishna B et al (2012) [9] 1 60 Male GC+HCC Hypertensive; right hydropneumothorax P/D AC; W-M/D HCC DG+LLS Uneventful No follow-up
Wang Y et al (2014) [4] 1 58 Male GC+HCC Hepatitis B P/D AC; HCC DG + Partial hepatectomy Uneventful Normal in the follow-up after one year
Ferreira E Mora H et al (2015) [10] 1 76 Male GIST+HCC Minor depression Gastrointestinal stromal tumors; HCC Atypical gastrectomy + left lobectomy Uneventful Normal in the follow-up after 30 mos
Wang C et al (2018) [11] 1 68 Male GC+HCC Tuberculosis; hepatitis B P/D AC; M-P/D HCC DG + Segmentectomy + RHVT Uneventful Normal in the follow-up after 9 mos
Hammami A et al (2020) [12] 1 50 Male GC+HCC No chronic illness P/D AC; HCC TG+TACE Uneventful Normal in the follow-up after 2 years

Abbreviations: P/D, poorly differentiated; M-P/D, moderately-to-poorly differentiated; W-M/D, well-to-moderately differentiated; M/D, moderately differentiated; W/D, well differentiated; AC, adenocarcinoma; DG, distal gastrectomy; STG, Subtotal gastrectomy; TG, total gastrectomy; LLS, left lateral sectionectomy; WR, wedge resection; mos, months; RHVT, right hepatic vein thrombectomy; CC, cholangiocarcinoma; GNEC, gastric neuroendocrine carcinoma.