Table 2. HRs of all-cause and cause-specific mortalities according to C-reactive protein levels in cohort participants.
| C-reactive protein | Person-years | Death cases | Mortality (1/1000 person-years) |
Crude HR (95% CI) | P value | Adjusted HR* (95% CI) | P value |
|---|---|---|---|---|---|---|---|
| All-cause mortality | |||||||
| <1 mg/L | 72 821 | 585 | 8.03 | ref. | ref. | ||
| 1–3 mg/L | 13 292 | 177 | 13.32 | 1.67 (1.42 to 1.98) | <0.001 | 1.29 (1.09 to 1.53) | 0.003 |
| >3 mg/L | 8961 | 158 | 17.63 | 2.23 (1.87 to 2.66) | <0.001 | 1.53 (1.28 to 1.83) | <0.001 |
| Cardiovascular mortality | |||||||
| <1 mg/L | 72 821 | 244 | 3.35 | ref. | ref. | ||
| 1–3 mg/L | 13 292 | 73 | 5.49 | 1.68 (1.29 to 2.18) | <0.001 | 1.22 (0.94 to 1.58) | 0.139 |
| >3 mg/L | 8961 | 75 | 8.37 | 2.58 (1.99 to 3.34) | <0.001 | 1.71 (1.32 to 2.22) | <0.001 |
| Cancer mortality | |||||||
| <1 mg/L | 72 821 | 182 | 2.50 | ref. | ref. | ||
| 1–3 mg/L | 13 292 | 58 | 4.36 | 1.79 (1.33 to 2.41) | <0.001 | 1.51 (1.12 to 2.03) | 0.007 |
| >3 mg/L | 8961 | 42 | 4.69 | 1.98 (1.41 to 2.77) | <0.001 | 1.56 (1.11 to 2.18) | 0.010 |
*
Adjusted for age, sex, area, marriage status, education, current smoking, alcohol consumption, physical activity, body mass index, systolic blood pressure, diastolic blood pressure, type 2 diabetes, dyslipidaemia and chronic kidney disease.