Table 1.
Disease-Chromosome Transmissions in the CMMT Database[Note]
|
No. of Cases |
||
| Parental Source of Transmissionand Status of Offspring | Parent Affected | Parent Unaffected |
| Paternal: | ||
| Affected | 88 | 8 |
| Unaffected: | ||
| CAG ⩾36 | 93 | 17 |
| CAG <36 | 68 | 16 |
| DNA unavailablea | 171 | 8 |
| Maternal: | ||
| Affected | 90 | 0 |
| Unaffected: | ||
| CAG ⩾36 | 123 | 8 |
| CAG <36 | 121 | 7 |
| DNA unavailablea | 244 | 3 |
| Sex of parent unknown: | ||
| Affected | 9 | 0 |
| Unaffected: | ||
| CAG ⩾36 | 12 | 2 |
| CAG <36 | 7 | 1 |
| DNA unavailablea | 13 | 1 |
Note.— In this table, we show all cases in which the parent has a chromosome with CAG ⩾36, as well as those in which the parental chromosome has given rise to a new mutation in one of his or her children. When the offspring has CAG <36, this generally represents a case of nontransmisssion of the disease chromosome.
a
Offspring has been entered into the database but, as yet, has not requested genetic testing through the CMMT.