Table 1.

Clinical Features of Representative Patients Selected for Genomewide Scan

	Age(years)
Patient	When Studied	At Diagnosis	Statusa	Total Serum Alkaline Phosphatase(×ULN)b	Radiological Features	No. of Bone Sites Affected	Total Pagetic Bonec(%)
DD-003	77	…	N	Normal	Normal	0	0
DD-004	76	48	+	25.2	Paget	31	37
DD-019	73	70	+	.5	Paget	2	16
DD-021	71	67	+	.7	Paget	1	3
DD-033	53	49	+	.5	Paget	4	5
TH-019	55	43	+	1.0	Paget	3	7
TH-102	64	60	+	1.6	Paget	15	53
TH-111	83	58	+	20.3	Paget	14	64
TH-143	52	46	+	11.8	Paget	26	31
LF-010	57	54	+	1.0	Paget	6	20
LF-019	80	…	N	Normal	Normal	0	0
LF-045	78	68	+	3.7	Paget	7	36
LF-074	74	46	+	4.4	Paget	16	64

^aAs described in the Patients, Material, and Methods section. N = normal; + = Paget disease of bone.

^bULN = upper limit of normal range, as determined by each clinical laboratory.

^cCalculated by use of Rénier et al.'s (1995) index.