Table 3.
Type I Error Rates of the Four Tests (T, QSAT, TDTMK, and TDTVC) in Simulations based on Empirical Population Genetics Data, under the Selective Sampling Scheme
|
Type I Error Rate(%) |
||||||||
|
P=.05 |
P=.01 |
|||||||
| No. of Independent Markers,Status of High-Risk Allele,and Trait Distribution | T | QSAT | TDTMK | TDTVC | T | QSAT | TDTMK | TDTVC |
| 520: | ||||||||
| Fixed: | ||||||||
| Normal | 22.5 | 4.5 | 4.9 | 5.2 | 12.1 | .80 | 1.42 | 1.12 |
| Log-normal | 18.9 | 4.3 | 4.3 | 4.2 | 9.0 | .74 | .88 | .68 |
| Random: | ||||||||
| Normal | 22.3 | 4.5 | 4.8 | 5.5 | 11.7 | .81 | .92 | 1.20 |
| Log-normal | 19.6 | 4.5 | 5.4 | 5.4 | 8.40 | .98 | 1.30 | 1.25 |
| 1,040: | ||||||||
| Fixed: | ||||||||
| Normal | 22.6 | 4.6 | 4.8 | 5.1 | 11.7 | .84 | .91 | .98 |
| Log-normal | 19.4 | 4.5 | 4.6 | 4.9 | 9.2 | .84 | .88 | .85 |
| Random: | ||||||||
| Normal | 22.0 | 4.9 | 5.5 | 5.3 | 11.7 | .95 | 1.36 | 1.22 |
| Log-normal | 18.6 | 4.3 | 5.8 | 5.7 | 9.5 | .81 | 1.25 | 1.05 |