1. IC50 for Compounds Tested against DnaK, 70S Ribosome, and DNA Gyrase.
compound tested: IC50 |
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enzyme | oncocin | N-cipro-oncocin | oncocin-cipro-c | ciprofloxacin | oncocin + cipro |
DnaK | 1.54 ± 0.08 μM | 1.01 ± 0.07 μM | 0.99 ± 0.06 μM | n/a | n/a |
70S ribosome | 66.7 ± 6.0 nM | 482.6 ± 89.2 nM | 51.1 ± 8.5 nM | n/a | n/a |
DNA gyrase | >10 μM | >10 μM | 2.5 μM | 0.3 μM | 0.3 μM |