Figure 1.

Unweighted reduced median network (Bandelt et al. 1995) of the 47 L2 samples from the Dominican Republic, showing the four clades L2a–L2d. The circles represent combined high-resolution RFLP and HVS-I haplotypes, with their areas proportional to the frequency. The smallest circles are singletons, whereas the largest have frequency 5. The black circles denote the four mtDNAs (one for each clade) that have been completely sequenced. RFLP mutations are indicated next to the branches, with the arrow pointing in the direction of a site gain. The label is the nucleotide at the beginning of the recognition sequence (in the numbering of the reference sequence of Anderson et al. [1981]); the letter suffix indicates the enzyme (see table 1). HVS-I mutations (between 16003 and 16474) are shown on the branches; they are transitions unless the base change is explicitly indicated. Underlining indicates resolved recurrent mutations, and unresolved events are shown by reticulation. Implausible links are shown with a dotted line. The node marked with an asterisk (*) has the RFLP motif +3592h, +10394c, −10871z, +16390g/−16390b and the HVS-I motif 223-278-390. The lengths of branches in L2a and L2d are shown distorted, for convenience of display. The hypervariable RFLP 16517e was not considered, nor were indel events.