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. 2025 Aug 15;16:181. doi: 10.1186/s13244-025-02058-7

Fig. 4.

Fig. 4

Proliferative prognostic imaging features. a HCC in a 50-year-old woman with autoimmune hepatitis. Axial T2-weighted fat-saturated MR image of a large 6.3-cm mass found in segment VIII. No histologic diagnosis was available. b HCC in a 75-year-old man with chronic hepatitis B viral infection without cirrhosis. Axial T1-weighted portal phase MR image of a mass with nonperipheral washout in segment VIII. Histologic diagnosis was a moderately differentiated HCC without microvascular invasion. c HCC in a 72-year-old male patient with chronic hepatitis B viral infection without cirrhosis. Axial T1-weighted arterial phase MR image of non-enhancing necrotic components within a large solid mass in segments V, VI, VII, and VIII. Histologic diagnosis confirmed a moderately differentiated HCC with microvascular invasion. d A 20-year-old woman with metabolic dysfunction-associated steatotic liver disease. On the T1-weighted hepatobiliary phase, the lesion is mildly hypointense compared to the surrounding liver parenchyma. Histologic diagnosis was an atypical hepatocellular neoplasm. e HCC in a 62-year-old man with alcohol-associated liver disease. Axial T1-weighted arterial phase MR image of multicentric hypointense lesions within the right liver with enhancement of the surrounding parenchyma. No histologic diagnosis was available. f HCC in an 83-year-old man with metabolic alcohol-associated liver disease. Axial portal phase CT image of a large multinodular infiltrative 9.0-cm mass found in segment IV. Histologic diagnosis was a poorly differentiated hepatocellular carcinoma