Fig. 9.

Case example of non-proliferative imaging features. HCC in a 58-year-old man with alcohol-associated liver disease. a Axial non-contrast T1-weighted MR image shows isointensity compared to the surrounding liver parenchyma. b Arterial phase image shows enhancement with (c) portal phase washout. d Axial in-phase and (e) out-of-phase images show a drop in intensity in out-of-phase imaging representing fat content. f Histologic diagnosis was a well-differentiated HCC. Two other fibrotic HCC lesions were identified, demonstrating complete treatment response (bottom left). H&E, hematoxylin and eosin