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. 2025 Aug 12;19:2709–2718. doi: 10.2147/OPTH.S541618

Table 2.

Comparison of Treatments for Dry Eye Disease by Baseline Cataract Status

Treatments for Dry Eye Disease* No History
(n = 646 Eyes)
On-Going
(n = 244 Eyes)
Pseudophakic/Aphakic
(n= 180 Eyes)
P-value
Artificial tears or gel 490 (75.9%) 191 (78.3%) 167 (92.8%) 0.001
Cyclosporine drops 89 (13.8%) 66 (27.0%) 55 (30.6%) <0.0001
Warm lid soaks 125 (19.3%) 57 (23.4%) 46 (25.6%) 0.16
Lid scrubs or baby shampoo 94 (14.6%) 38 (15.6%) 34 (18.9%) 0.38
Lubricating Ointment 64 (9.9%) 25 (10.2%) 39 (21.7%) 0.030
Punctal plugs in place 71 (11.0%) 25 (10.2%) 32 (17.8%) 0.24
Steroid eye drops or ointments 19 (2.9%) 9 (3.7%) 8 (4.4%) 0.49
Prescription pills 20 (3.1%) 10 (4.1%) 2 (1.1%) 0.59
Autologous serum eye drops 12 (1.9%) 6 (2.5%) 2 (1.1%) 0.87
Other OTC treatment 27 (4.2%) 21 (8.6%) 12 (6.7%) 0.13
Any Other treatment 68 (10.5%) 19 (7.8%) 17 (9.4%) 0.51

Notes: *Participants can take more than 1 treatment for DED at the same time. Bold values indicate statistical significance (P<0.05).