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Inhibition of tyrosine phosphorylation of STAT1 and STAT2 in response to IFN-α and IFN-γ by LGTV (strain TP21). Uninfected Vero cells or cells infected with LGTV for 48 h were treated with IFN-α or IFN-γ for 15 min or left untreated. The cell lysates were examined by Western blotting (shown in duplicate) with antibodies to STAT1, Tyr701-phosphorylated STAT1 (pY-STAT1), STAT2, or Tyr689-phosphorylated STAT2 (pY-STAT2; arrow), as indicated to the left of each panel.
