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. 2025 Aug 13;18:10969–10994. doi: 10.2147/JIR.S532630

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© 2025 Pan et al.

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LPJZD induces mitophagy in MASH liver cells. (A) Western blot analysis was performed to determine the protein expression levels of PINK1, Parkin, and GPx4. (B–D): Quantification of protein expression levels of PINK1, Parkin, and GPx4. (E) Evaluation of the effect of LPJZD on mitochondrial autophagosomes using transmission electron microscopy (×10000). (F) Quantification of the mitophagosome number. (G) Evaluation of the effect of LPJZD on MMP. (H) Quantification of the effect of LPJZD on MMP. Data from three independent replicates are presented as the mean ± SD. ** P < 0.01.