Table 2.
Clinical characteristics of study participants according to patients with and without sICH.
| Variables | With sICH, n = 82 | Without sICH, n = 653 | P value |
|---|---|---|---|
| Demographic characteristics | |||
| Age, years | 72.2 ± 9.9 | 71.18 ± 11.0 | 0.405 |
| Male, n (%) | 50 (61.0) | 382 (58.5) | 0.668 |
| Vascular risk factors, n (%) | |||
| Hypertension | 66 (80.5) | 497 (76.1) | 0.378 |
| Diabetes mellitus | 39 (47.6) | 286 (44.1) | 0.525 |
| Hyperlipidemia | 8 (9.1) | 80 (90.1) | 0.512 |
| Coronary heart disease | 17 (14.6) | 112 (20.7) | 0.422 |
| Smoking | 32 (39.0) | 253 (38.7) | 0.894 |
| Clinical data | |||
| Systolic blood pressure, mmHg | 141.8 ± 22.0 | 139.0 ± 22.5 | 0.278 |
| Diastolic blood pressure, mmHg | 83.3 ± 13.6 | 84.5 ± 13.9 | 0.486 |
| Time from onset to recanalization, min | 376.5 (253.8, 533.0) | 354.5 (240.0, 556.3) | 0.746 |
| Baseline NIHSS, score | 15.0 (11.0, 19.0) | 13.0 (10.0, 18.0) | 0.044 |
| Baseline ASPECTS, score | 8.0 (8.0, 9.0) | 9.0 (8.0, 10.0) | 0.003 |
| Stroke subtypes, n (%) | 0.226 | ||
| Atherosclerotic | 43 (52.4) | 290 (44.4) | |
| Cardioembolic | 33 (40.2) | 279 (42.7) | |
| Others | 6 (7.3) | 84 (12.9) | |
| Prior intravenous thrombolysis, n (%) | 38 (46.4) | 227 (34.8) | 0.040 |
| Poor collateral status, n (%) | 51 (62.2) | 277 (42.4) | 0.001 |
| Successful reperfusion, n (%) | 72 (87.8) | 602 (92.2) | 0.175 |
| Number of stent-retriever passes | 1.7 ± 1.3 | 1.5 ± 1.2 | 0.176 |
| Vascular occlusion site, n (%) | 0.338 | ||
| Middle cerebral artery | 52 (63.4) | 445 (68.1) | |
| Internal carotid artery | 30 (36.6) | 208 (31.9) | |
| Laboratory parameters | |||
| Fasting blood glucose, mmol/l | 8.2 ± 2.4 | 7.1 ± 2.4 | 0.001 |
| Hemoglobin, g/L | 124.9 ± 19.4 | 129.4 ± 19.7 | 0.046 |
| Lymphocyte, 10^9/L | 1.1 ± 0.4 | 1.2 ± 0.6 | 0.075 |
| Albumin, g/L | 36.7 ± 4.5 | 37.3 ± 3.5 | 0.327 |
| Platelet count, 10^9/L | 191.3 ± 48.5 | 186.3 ± 53.9 | 0.422 |
| HALP score | 26.4 ± 13.4 | 32.8 ± 19.8 | 0.001 |
sICH, Symptomatic Intracranial Hemorrhage; mRS, Modified Rankin Scale; NIHSS, National Institute of Health stroke scale; ASPECTS, the Alberta Stroke Program Early Computed Tomography Score; TOAST, Trial of Org 10,172 in Acute Stroke Treatment; HALP, index combined by hemoglobin, albumin, lymphocyte and platelet.