TABLE 2.
Demographic and clinical characteristics of maintenance hemodialysis patients.
| Baseline characteristics | All patients N = 210 |
Insomnia | P | Pruritus | P | Constipation | P | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Yes N = 114 |
No N = 96 |
Yes N = 86 |
No N = 124 |
Yes N = 36 |
No N = 174 |
|||||
| Men, n (%) | 138 (65.71%) | 76 (66.67%) | 62 (64.58%) | 0.751 | 62 (72.09%) | 76 (61.30%) | 0.105 | 25 (69.44%) | 113 (64.94%) | 0.604 |
| Diabetes, n (%) | 82 (39.05%) | 45 (39.48%) | 37 (38.54%) | 0.890 | 29 (33.72%) | 53 (42.74%) | 0.188 | 17 (47.22%) | 65 (37.35%) | 0.269 |
| Hypertension, n (%) | 184 (87.62%) | 100 (8.72) | 84 (87.50%) | 0.962 | 74 (86.04%) | 110 (88.71%) | 0.564 | 36 (91.67%) | 151 (86.78%) | 0.418 |
| Cardiac diseasen, n (%) | 57 (27.14%) | 32 (28.07%) | 25 (26.04%) | 0.742 | 18 (20.93%) | 39 (31.45%) | 0.092 | 10 (27.78%) | 47 (27.01%) | 0.925 |
| AVF, n (%) | 181 (86.20%) | 101 (88.60%) | 80 (83.33%) | 0.271 | 76 (88.37%) | 105 (84.68%) | 0.445 | 30 (83.33%) | 151 (86.78%) | 0.585 |
| Age (year) | 56.29 ± 13.27 | 56.26 ± 11.30 | 56.31 ± 15.27 | 0.979 | 55.79 ± 12.41 | 56.63 ± 13.88 | 0.654 | 57.14 ± 13.31 | 56.11 ± 13.30 | 0.673 |
| Duration of MHD (months) | 59.05 ± 47.29 | 56.87 ± 44.70 | 61.65 ± 50.30 | 0.726 | 58.3 ± 48.78 | 59.57 ± 46.42 | 0.714 | 54.03 ± 44.67 | 60.09 ± 47.87 | 0.513 |
| Dialysis time per week (hours) | 11.27 ± 1.37 | 11.18 ± 1.42 | 11.38 ± 1.30 | 0.269 | 11.16 ± 1.39 | 11.35 ± 1.36 | 0.532 | 11.47 ± 1.10 | 11.23 ± 1.42 | 0.569 |
| Dry weight (kg) | 62.4 ± 13.41 | 62.19 ± 12.55 | 62.65 ± 14.42 | 0.958 | 62.43 ± 12.28 | 62.38 ± 14.18 | 0.771 | 66.04 ± 13.11 | 61.65 ± 13.38 | 0.024 |
| UF volume (ml) | 2728.11 ± 831.54 | 2763.10 ± 850.24 | 2668.56 ± 811.24 | 0.508 | 2899.03 ± 748.99 | 2609.57 ± 867.55 | 0.013 | 2816.76 ± 779.07 | 2709.77 ± 842.96 | 0.484 |
| UF rate (mL/min) | 11.71 ± 3.58 | 11.91 ± 3.66 | 11.47 ± 3.47 | 0.368 | 12.50 ± 3.25 | 11.17 ± 3.70 | 0.008 | 12.20 ± 3.36 | 11.61 ± 3.62 | 0.372 |
| SpKt/V | 1.31 ± 0.25 | 1.30 ± 0.23 | 1.31 ± 0.27 | 0.669 | 1.283 ± 0.24 | 1.323 ± 0.26 | 0.235 | 1.24 ± 0.22 | 1.32 ± 0.26 | 0.100 |
| Hb (g/L) | 109.75 ± 16.75 | 109.19 ± 17.22 | 110.42 ± 16.23 | 0.599 | 107.873 ± 18.72 | 111.06 ± 15.18 | 0.176 | 39.68 ± 2.94 | 39.44 ± 3.16 | 0.983 |
| K (mmol/L) | 39.48 ± 3.11 | 4.76 ± 0.71 | 4.73 ± 0.63 | 0.793 | 4.83 ± 0.66 | 4.693 ± 0.68 | 0.198 | 4.73 ± 0.60 | 4.75 ± 0.69 | 0.953 |
| Ca (mmol/L) | 2.21 ± 0.23 | 2.24 ± 0.26 | 2.17 ± 0.18 | 0.029 | 2.22 ± 0.25 | 2.20 ± 0.23 | 0.423 | 2.23 ± 0.24 | 2.20 ± 0.23 | 0.724 |
| P (mmol/L) | 2.00 ± 0.53 | 2.04 ± 0.55 | 1.9 ± 0.50 | 0.210 | 2.06 ± 0.47 | 1.96 ± 0.56 | 0.140 | 1.97 ± 0.41 | 2.01 ± 0.55 | 0.698 |
| Na (mmol/L) | 136.50 ± 3.39 | 136.50 ± 3.39 | 136.36 ± 3.48 | 0.428 | 136.79 ± 3.40 | 136.31 ± 3.39 | 0.277 | 136.94 ± 3.12 | 136.41 ± 3.45 | 0.62 |
| Cl (mmol/L) | 95.94 ± 4.00 | 95.94 ± 4.00 | 95.79 ± 4.29 | 0.546 | 96.08 ± 4.14 | 95.85 ± 3.92 | 0.677 | 96.47 ± 4.00 | 95.83 ± 4.01 | 0.385 |
| Mg (mmol/L) | 1.09 ± 0.14 | 1.10 ± 0.15 | 1.08 ± 0.14 | 0.363 | 1.11 ± 0.13 | 1.08 ± 0.15 | 0.144 | 1.07 ± 0.16 | 1.10 ± 0.14 | 0.292 |
| CO2CP(mmol/L) | 19.52 ± 2.60 | 19.42 ± 2.50 | 19.65 ± 2.72 | 0.511 | 19.49 ± 2.43 | 19.55 ± 2.73 | 0.864 | 19.68 ± 2.34 | 19.49 ± 2.66 | 0.704 |
| Uric acid (μmol/L) | 443.86 ± 96.04 | 450.20 ± 101.11 | 436.92 ± 89.60 | 0.426 | 458.11 ± 99.54 | 433.97 ± 92.66 | 0.052 | 430.22 ± 93.33 | 446.68 ± 96.62 | 0.48 |
| iPTH (pmol/L) | 49.69 ± 49.00 | 44.96 ± 38.44 | 55.31 ± 58.87 | 0.187 | 46.69 ± 40.18 | 51.77 ± 54.35 | 0.452 | 62.82 ± 64.93 | 46.98 ± 44.77 | 0.271 |
| hs-CRP (mg/L) | 4.38 ± 6.36 | 4.70 ± 7.21 | 4.00 ± 5.18 | 0.983 | 4.33 ± 5.72 | 4.41 ± 6.79 | 0.534 | 3.71 ± 5.45 | 4.52 ± 6.54 | 0.213 |
| Albumin (g/L) | 39.48 ± 3.11 | 39.67 ± 2.85 | 39.25 ± 3.40 | 0.457 | 40.06 ± 2.87 | 39.08 ± 3.23 | 0.067 | 39.68 ± 2.94 | 39.44 ± 3.16 | 0.870 |
| Prealbumin (mg/L) | 352.62 ± 82.54 | 352.62 ± 82.54 | 359.78 ± 87.70 | 0.172 | 360.53 ± 81.83 | 347.14 ± 82.92 | 0.248 | 39.68 ± 2.94 | 39.44 ± 3.16 | 0.607 |
| β2-MG (mg/L) | 29.24 ± 6.66 | 30.06 ± 6.91 | 28.26 ± 6.244 | 0.055 | 30.04 ± 6.00 | 28.69 ± 7.05 | 0.186 | 28.03 ± 6.83 | 29.49 ± 6.62 | 0.064 |
| Ferritin (ng/mL) | 319.14 ± 569.08 | 306.55 ± 428.49 | 334.08 ± 702.62 | 0.903 | 431.96 ± 814.66 | 240.89 ± 276.74 | 0.551 | 218.05 ± 258.01 | 340.05 ± 612.54 | 0.192 |
| WBC(×109/L) | 6.47 ± 1.89 | 6.40 ± 1.75 | 6.54 ± 2.05 | 0.726 | 6.29 ± 1.91 | 6.59 ± 1.88 | 0.145 | 6.72 ± 2.19 | 6.41 ± 1.83 | 0.534 |
| PLT (×109/L) | 196.49 ± 65.66 | 195.59 ± 71.04 | 197.55 ± 58.99 | 0.615 | 191.19 ± 68.43 | 200.16 ± 63.69 | 0.191 | 189.97 ± 64.57 | 197.83 ± 65.99 | 0.582 |
| Pre-dialysis Cr (μmol/L) | 997.39 ± 239.39 | 1019.08 ± 247.53 | 971.62 ± 227.94 | 0.161 | 1063.13 ± 199.02 | 951.79 ± 254.73 | 0.002 | 990.72 ± 225.57 | 998.76 ± 242.75 | 0.819 |
| Pre-dialysis Urea (mmol/L) | 25.12 ± 6.50 | 25.13 ± 6.52 | 25.11 ± 6.52 | 0.965 | 25.88 ± 6.15 | 24.6 ± 6.71 | 0.091 | 23.33 ± 5.31 | 25.49 ± 6.68 | 0.055 |
| Post-dialysis Cr (μmol/L) | 392.99 ± 126.36 | 402.55 ± 131.45 | 381.63 ± 119.72 | 0.261 | 418.37 ± 117.95 | 375.39 ± 129.43 | 0.012 | 410.39 ± 116.85 | 389.39 ± 128.26 | 0.292 |
| Post-dialysis Urea (mmol/L) | 8.78 ± 3.37 | 8.69 ± 3.41 | 8.86 ± 3.34 | 0.561 | 9.21 ± 3.21 | 8.48 ± 3.45 | 0.035 | 8.60 ± 2.66 | 8.82 ± 3.50 | 0.906 |
| Cr clearance (μmol/L) | 602.76 ± 157.16 | 613.52 ± 160.63 | 589.99 ± 152.79 | 0.147 | 640.65 ± 142.92 | 576.48 ± 161.72 | 0.001 | 570.53 ± 162.72 | 609.43 ± 155.63 | 0.176 |
| Urea clearance (mmol/L) | 16.34 ± 4.15 | 16.27 ± 4.07 | 16.42 ± 4.25 | 0.909 | 16.67 ± 3.97 | 16.11 ± 4.27 | 0.321 | 14.72 ± 3.61 | 16.68 ± 4.19 | 0.005 |
| Insomnia | 112 (53.33%) | — | — | — | 56 (65.11%) | 58 (46.78%) | 0.009 | 27 (75.00%) | 9 (50.00%) | 0.006 |
| Pruritus | 86 (40.95%) | 56 (49.12%) | 30 (31.25%) | 0.009 | — | — | — | 17 (47.22) | 69 (39.66) | 0.401 |
| Constipation | 36 (17.14%) | 27 (23.68%) | 9 (9.38%) | 0.006 | 17 (19.77%) | 19 (15.32%) | 0.401 | — | — | — |
BMI, body mass index; AVF, arteriovenous fistulas; MHD, maintenance hemodialysis patient; UF, ultrafiltration; SpKt/V, single-pool hemodialysis adequacy; Hb, hemoglobin; Ca, calcium; P, phosphate; Na, sodium; Cl, chloride; Mg, Magnesium; CO2CP, carbon dioxide combining pow; iPTH, intact parathyroid hormone; hs-CRP, high-sensitivity C-reactive protein; β2-MG, beta 2-microglobulin; WBC, white blood cell count; PLT, platelet count; Cr, creatinine.