Table 2.
Associations between dichotomized clinical condition and immunohistological results
‘Back pain+’ is defined as NRS≥4; ‘Leg pain+’ is defined as NRS≥4; ‘ODI +’ is defined as ODI≥24; 158 patients filled in the questionnaires on leg pain and 154 patients filled in the questionnaires on back pain and ODI: therefore percentages were also indicated of patients with severe back/leg pain of ODI for each inflammation subgroup. In the no MF group 1 case was missing for ODI, in the M1 dominant group 2 cases were missing for back pain and ODI, for M1 = M2 group, 1 case was missing in for back pain and ODI; ∗ P-value <0.05
| Back pain+ (n = 95) N (%) |
Leg pain+ (n = 142) N (%) |
ODI+ (n = 139) N (%) |
|
|---|---|---|---|
| Inflammation severity | |||
| Minimal (N = 63) | 24/50 (48 %) | 42/51 (82 %) | 44/50 (88 %) |
| Considerable (N = 124) | 71/104 (68 %) | 100/107 (93 %) | 95/104 (91 %) |
| p-value | 0.021∗ | 0.046∗ | 0.566 |
| Macrophage type (N = total) | |||
| M1 dominant (N = 89) | 51/73 (70 %) | 68/75 (91 %) | 66/75 (88 %) |
| M1 = M2 (N = 28) | 18/23 (78 %) | 23/24 (96 %) | 22/24 (92 %) |
| M2 dominant (N = 17) | 9/16(56 %) | 16/16 (100 %) | 15/16 (94 %) |
| No MF (N = 55) | 17/43 (40 %) | 35/44 (81 %) | 36/43 (84 %) |
| p-value | 0.005∗ | 0.169 | 0.252 |