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. 2025 Aug 6;5:104388. doi: 10.1016/j.bas.2025.104388

Table 5.

Correlation between baseline clinical condition and macrophage type in MC subgroups

‘Back pain+’ is defined as NRS≥4; ‘Leg pain+’ is defined as NRS≥4; ‘ODI +’ is defined as ODI≥24; N = available/total; Fisher's exact test was used for comparisons between groups; ∗ P-value <0.05

Back pain+
N (%)
Leg pain+
N (%)
ODI+
N (%)
No MC
M1 dominant (N = 39/49) 24 (62 %) 37 (93 %) 35 (90 %)
M1 = M2 (N = 12/16) 9 (75 %) 12 (100 %) 12 (100 %)
M2 dominant (N = 10/10) 6 (60 %) 10 (100 %) 9 (90 %)
No MF (N = 22/29) 11 (50 %) 15 (65 %) 17 (77 %)
p-value 0.590 0.006∗ 0.275
With MC I
M1 dominant (N = 9/12) 7 (78 %) 8 (89 %) 7 (78 %)
M1 = M2 (N = 2/2) 2 (100 %) 1 (50 %) 2 (100 %)
M2 dominant (N = 1/1) 1 (100 %) 1 (100 %) 1 (100 %)
No MF (N = 1/1) 1 (100 %) 1 (100 %) 1 (100 %)
p-value 1.000 0.538 1.000
With MC II
M1 dominant (N = 25/28) 20 (80 %) 23 (88 %) 24 (96 %)
M1 = M2 (N = 9/10) 7 (78 %) 9 (100 %) 8 (89 %)
M2 dominant (N = 5/6) 2 (40 %) 5 (100 %) 5 (100 %)
No MF (N = 19/25) 5 (26 %) 19 (100 %) 18 (95 %)
p-value 0.001∗ 0.447 0.815