Table 4.

The association of herpes zoster and all infections with incident giant cell arteritis stratified by time period prior to index date

Empty Cell	Herpes zoster infection		Any infection
Empty Cell	Adjusted IRR (95% CI)*	p Value	Adjusted IRR (95% CI)*	p Value
<1 year†	1.32 (0.95 to 1.82)	0.10	1.66 (1.54 to 1.79)	<0.01
1–2 years	1.11 (0.79 to 1.56)	0.55	1.32 (1.22 to 1.43)	<0.01
2–3 years	1.00 (0.70 to 1.43)	0.99	1.19 (1.09 to 1.29)	<0.01
3–4 years	0.92 (0.63 to 1.36)	0.69	1.19 (1.09 to 1.30)	<0.01
4–5 years	1.15 (0.77 to 1.70)	0.49	1.14 (1.05 to 1.25)	<0.01
5–10 years	1.36 (1.14 to 1.64)	<0.01	1.26 (1.17 to 1.35)	<0.01
>10 years	1.18 (0.99 to 1.42)	0.07	1.22 (1.13 to 1.32)	<0.01

^*Adjusted for Charlson Comorbidity Index, alcohol use, smoking history, prior use of immunosuppressive therapies and prior use of oral glucocorticoids.

^†Including 6 months prior to index date.

IRR, incident rate ratio.