Table 4. Multiplicative and additive interactions between childhood health and childhood SES on dementia risk.
| Interaction type | Measure | Estimate (95% CI) | P value |
|---|---|---|---|
| Multiplicative interaction (OR scale) | |||
| Unhealthy childhood (without interaction) | 1.27 (0.99 to 1.63) | 0.061 | |
| Poor SES (without interaction) | 1.42 (1.00 to 2.01) | 0.048 | |
| Unhealthy childhood (with interaction) | 1.44 (0.51 to 4.09) | 0.496 | |
| Poor SES (with interaction) | 1.44 (1.00 to 2.09) | 0.052 | |
| Interaction term | 0.88 (0.30 to 2.57) | 0.809 | |
| Additive interaction (coefficient scale) | |||
| RERI | −0.06 (−1.59 to 1.47) | 0.935 | |
| AP | −0.04 (−0.88 to 0.81) | 0.935 | |
| S | 0.93 (−0.68 to 2.54) | 0.259 |
AP, attributable proportion; RERI, relative excess risk due to interaction; S, synergy index; SES, socioeconomic status.