Table 5.
Linear mixed-effect model results for viral load count.
| Variables | Categories | Estimate (β) | Standard error | p value |
|---|---|---|---|---|
| Intercept | — | 1086.153 | 943.705 | 0.0250∗ |
|
| ||||
| Baseline viral load count (ref = < 10,000 copies/mL) | ≥ 10,000 copies/mL | 465.1111 | 152.992 | 0.0026∗ |
|
| ||||
| Hemoglobin (ref = < 11 g/dL) | ≥ 11 g/dL | −493.466 | 308.503 | 0.0107∗ |
|
| ||||
| Adherence (ref = poor) | Fair | −175.8583 | 190.5431 | 0.3058 |
| Good | 48.8828 | 207.7299 | 0.8143 | |
|
| ||||
| WHO (ref = stage-I) | Stage-II | 129.2140 | 175.7851 | 0.4629 |
| Stage-III | −37.4238 | 199.7453 | 0.8515 | |
| Stage-IV | 259.0464 | 285.0798 | 0.3064 | |
|
| ||||
| CD4 cell (Ref = < 200 cells/mm3) | ≥ 200 cells/mm3 | −38.1656 | 329.039 | 0.0027∗ |
|
| ||||
| OIs (ref = no) | Yes | 25.0131 | 297.0715 | 0.3030 |
|
| ||||
| INH (ref = No) | Yes | 54.7061 | 187.6115 | 0.7710 |
|
| ||||
| CPT | Yes | −326.7697 | 155.3603 | 0.0363∗ |
|
| ||||
| ART regiment (Ref = 1day) | 1c | −61.0715 | 172.8141 | 0.7240 |
| 1e | 112.9706 | 193.0467 | 0.5588 | |
| Others | 7.2122 | 200.0455 | 0.9713 | |
|
| ||||
| Functional status (Ref = working) | Ambulatory | −60.2005 | 182.0894 | 0.7412 |
| Bedridden | 416.0007 | 219.3561 | 0.0059∗ | |
|
| ||||
| Weight (ref = < 50 kg) | ≥ 50 kg | −212.4409 | 153.7031 | 0.1679 |
|
| ||||
| BMI (ref = < 18.5 kg/m2) | 18.5–24.9 kg/m2 | −83.8169 | 172.3190 | 0.6270 |
| ≥ 25 kg/m2 | −187.5525 | 215.4093 | 0.3846 | |
|
| ||||
| OCC (ref = no) | Yes | 123.0448 | 273.2443 | 0.0028∗ |
|
| ||||
| TB type (ref = pulmonary) | Extrapulmonary | 430.2767 | 201.5426 | 0.0336∗ |
|
| ||||
| Hematocrit in % | — | 1.0774 | 19.4602 | 0.9559 |
|
| ||||
| WBC in 103/μL | — | 17.9035 | 37.5654 | 0.6340 |
|
| ||||
| RBC in 106/μL | — | −68.3277 | 72.5133 | 0.3468 |
|
| ||||
| Platelet in 103/μL | — | −2.4840 | 0.7019 | 0.0005∗ |
|
| ||||
| Monocyte in % | — | −13.5370 | 16.8024 | 0.4211 |
|
| ||||
| Lymphocyte in % | — | −7.9541 | 6.4649 | 0.0219∗ |
|
| ||||
| Visit time | — | −2.1586 | 0.2816 | 0.001∗ |
Note: g/dL indicates gram per deciliter, kg/m2 indicates kilogram per meter square, copies/mL indicates copies per milliliter, 1 day refers to ART treatment of AZT-3TC-EFV, 1c refers to ART treatment of AZT-3TC-NVP, 1e refers to TDF-3TC-EFV and other means other ART treatments, like 1j (TDF + 3 TC + DTG) and 1f (TDF+3 TC + NVP).
∗Statistically significant at 5% level of confidence.