Abstract
A viral agent was isolated from the fetal liver of an aborted equine fetus. The isolate hemagglutinated red blood cells from guinea pig, rhesus monkey and rooster. By hemagglutination inhibition tests, the isolate was shown to be antigenically distinct from parvoviruses of bovine and canine origin. Specific hemagglutination inhibiting antibody against the viral isolate was exhibited by 26 of 136 horse sera tested. The isolated virus showed properties compatible with those of an autonomous parvovirus including size, morphology, stability to ether treatment and heating to 56 degrees C, the presence of a 5300 base DNA genome, characteristic protein composition and density (1.405 g/mL). The virus was classified as an equine parvovirus.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bouillant A. M., Genest P., Greig A. S. Growth characteristics of a cell line derived from the pig oviduct. Can J Microbiol. 1975 Dec;21(12):2094–2097. doi: 10.1139/m75-299. [DOI] [PubMed] [Google Scholar]
- Hammond G. W., Hazelton P. R., Chuang I., Klisko B. Improved detection of viruses by electron microscopy after direct ultracentrifuge preparation of specimens. J Clin Microbiol. 1981 Aug;14(2):210–221. doi: 10.1128/jcm.14.2.210-221.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- King D. J., Hopkins S. R. Evaluation of the hemagglutination-inhibition test for measuring the response of chickens to avian infectious bronchitis virus vaccination. Avian Dis. 1983 Jan-Mar;27(1):100–112. [PubMed] [Google Scholar]
- Mayr A., Bachmann P. A., Siegl G., Mahnel H., Sheffy B. E. Characterization of a small porcine DNA virus. Arch Gesamte Virusforsch. 1968;25(1):38–51. doi: 10.1007/BF01243088. [DOI] [PubMed] [Google Scholar]
- Paradiso P. R. Infectious process of the parvovirus H-1: correlation of protein content, particle density, and viral infectivity. J Virol. 1981 Sep;39(3):800–807. doi: 10.1128/jvi.39.3.800-807.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Paradiso P. R., Rhode S. L., 3rd, Singer I. I. Canine parvovirus: a biochemical and ultrastructural characterization. J Gen Virol. 1982 Sep;62(Pt 1):113–125. doi: 10.1099/0022-1317-62-1-113. [DOI] [PubMed] [Google Scholar]