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. 2025 May 6;3(8):837–853. doi: 10.1021/envhealth.4c00245

3. Exposure Parameters and Formulas Used in Previous Literature.

Exposure pathways Formula No. Formulas Exposure parameters Reference
Inhalation a ADD=Cg+p×IR×EF×ED×FuptakenBW×AT ADD, average daily dose; C g+p, concentration of VMS in gaseous and aerosolized states (μg/m3); IR, inhalation rate (m3/day); EF, exposure frequency (days); ED, exposure duration (years), F uptaken, uptake fraction; BW, body weight (kg); AT, average time (day).
b E=C×IRair×AT×Fuptaken E, exposure; C, concentration in air (μg/m3); IRair, inhalation rate for adults (1.2 m3/h); AT, average time for 8 h per day spent in this industrial area (h); F uptaken, uptake fraction.
c DED=C×IR×EDBW DED, daily exposure dose; C, concentration in air (μg/m3); IR, inhalation rate (m3/day); ED, exposure duration (years); BW, body weight (kg).
d E=Fuptaken×(Cair×Vair+CPM2.5×QPM2.5)BW E, exposure; Fuptaken, uptake fraction; Cair, concentration in air (μg/m3); V air , volume of inhalation (m3/day); C PM2.5, concentration in PM2.5(μg/g); Q PM2.5, PM2.5 inhalation rate (g/d); BW, body weight (kg).
e Inhexp=CairVroom×IR×EDBW Inhexp, the daily inhalation exposure per capita; C air, concentration in air (μg/m3); V room, indoor air volume (m3); IR, inhalation rate (20 m3/day for adults and 5 m3/day for children); ED, exposure duration (day); BW, average body weight (kg).
Oral ingestion f EDI=C×ED×IR×EFBW×AT EDI, estimated daily intakes; C, concentration in dust (ng/g); ED, exposure duration (years); IR, dust ingestion rate (20 and 50 mg/day for adults and children with a normal exposure case, 50 and 200 mg/day for adults and children with a high exposure case); EF, exposure frequency (day/year); BW, average body weight (kg); AT, average time (day).
g ADD=C×ED×EF×Fing×QBW×AT ADD, average daily dose; C, concentrations of VMS (μg/g); ED, exposure duration (years); EF, exposure frequency (days); F ing, uptake fraction of the compound; Q, dust ingestion rate (g/day); BW, body weight (kg); AT, average time (day).
h EDI=C×R×PtimeBW EDI, estimated daily intakes; C, concentration of VMS (ng/g); R, daily dust intake rate (g/d); P time, percentage of the time that people spent in measured regions; BW, average body weight (kg).
i EDI=C×R×IEFBW EDI, estimated daily intakes; C, concentration of VMS (ng/g); R, daily dust intake rate (g/d); IEF, indoor exposure fraction (h/day); BW, average body weight (kg).
j E=Cdust×QdustBW E, exposure via ingestion; Cdust, concentration of VMS in indoor dust (μg/g); Q dust, dust ingestion rate (g/day).
k EDI=C×W×BIOBW EDI, estimated daily intakes; C, concentration of VMS (ng/g); W, daily intake rate (g/d); BIO, bioavailability, 1; BW, average body weight (kg).
l E=C×W×BIO×MFBW E, mouthing exposure; C, concentration of VMS in children’s products (μg/g); W, weight of the entire product; Bio, bioavailability, 1; MF, VMS in the product that can migrate to saliva; BW, body weight (kg).
Dermal exposure m DED=C×ABS×AF×SA×EFBW×CF DED, dermal exposure dose; C, concentration of VMS (μg/g); ABS, dermal adsorption fraction; AF, skin adherence factor (mg/cm2); SA, exposed surface area of skin (cm2/day); EF, exposure frequency (day/year); BW, average body weight (kg); CF, conversion factor (106 mg/kg).
n EDI=C×ABS×AF×SA×EF×EDBW×AT EDI, estimated daily intakes; C, concentration of VMS (μg/g); ABS, dermal adsorption fraction (0.03); AF, skin adherence factor (0.07 and 0.2 mg/cm2 for adults and children); SA, exposed surface area of skin (5700 and 2700 cm2 for adults and children, respectively); EF, exposure frequency (day/year); ED, exposure duration (years); BW, average body weight (kg); AT, average time (day).
o ADD=CPCPs_i×EF×ED×Fder×Ai×Fqi×RiBW×AT ADD, average daily dose; i, type of PCPs; C PCPs, concentrations PCPs (μg/g); EF, exposure frequency (days); ED, exposure duration (years); F der, fraction of the product that may be retained on the skin surface; A, amount of product used per application (g/event); F q , frequency of application (events/day); R, retention factor; BW, body weight (kg); AT, average time (day).