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. 2025 Jul 11;13(6):102285. doi: 10.1016/j.jvsv.2025.102285

Table II.

Efficacy and safety results for cryo-laser cryo-sclerotherapy (CLaCS) and foam

Outcomes No.a CLaCS Foam Bilat P valueb
Pigmentation on photo 21 7 (33.3) 5 (23.8) 3 .8906
Colorimetry ΔE >1 21 9 (42.8) 13 (61.9) 7 .1445
Colorimetry ΔE >2 21 3 (14.2) 7 (33.3) 2 .1094
Colorimetry ΔE >2 FP III/IV 20 2 (10) 7 (35) 2 .0312
Bruising D7 23 3 (13) 9 (39.1) 3 .0156
Micro thrombi/drainage 23 3 (13) 9 (39.1) 2 .0351
Matting 21 0 1 (4.7) 0 1
Scarring 21 1 (4.7) 0 0 1
Redness/topic reaction 23 2 (8.6) 2 (8.6) 2 1

Bilat, Patients that presented the outcome in both lower limbs; FP, Fitzpatrick skin type classification.

Data are presented as number (%).

a

No. varies due to participant loss to follow-up.

b

P value calculated using McNemar test.