Table 7.

Univariate and multivariate logistic regression analysis of predictors for malignancy in Bethesda III AUS thyroid nodules.

Predictor	Univariate OR	95% CI	p value	Multivariate OR (aOR)	95% CI	p value
Bethesda III subcategory
III-A (ref)	1	—	—	1	—	—
III-B	3.85	1.80–8.2	0.001	3.25	1.50–7.05	0.003
III-C	3.1	1.35–7.15	0.008	2.65	1.12–6.3	0.027
III-D	1.5	0.50–4.5	0.45	1.3	0.42–4.08	0.63
III-E	0.55	0.18–1.65	0.29	0.48	0.15–1.5	0.21
III-F	2.95	0.18–48.9	0.45	2.7	0.15–48	0.48
Age group
< 40 years (ref)	1	—	—	1	—	—
40–60 years	1.4	0.90–2.25	0.11	1.25	0.80–2.1	0.32
> 60 years	0.95	0.50–1.9	0.91	0.88	0.43–1.78	0.71
Family history of thyroid cancer
No (ref)	1	—	—	1	—	—
1st degree relative	2.2	1.10–4.45	0.026	1.9	0.95–3.9	0.067
2nd degree relative	1.3	0.65–2.6	0.45	1.15	0.55–2.42	0.71
No (ref)	1	—	—	1	—	—
Yes	1.85	0.65–5.2	0.25	1.6	0.55–4.65	0.38
Radiological findings
Microcalcification	1.95	1.20–3.15	0.006	1.8	1.05–3.1	0.031
Hypervascularity	1.1	0.70–1.75	0.67	1.05	0.65–1.7	0.83
Irregularity	4.75	1.05–21.5	0.043	4.2	0.90–19.6	0.067