Skip to main content
. 2025 Aug 6;16:1636158. doi: 10.3389/fimmu.2025.1636158

Figure 1.

Scatter plot comparing adipsin levels in two panels. Panel A shows groups: Healthy Controls, Early-RA, Established-RA, Axial-SpA with significant differences indicated by p-values. Panel B categorizes individuals by age: under fifty, fifty to sixty-four, and sixty-five or older, with significant p-values noted.

Serum adipsin levels. (A) Adipsin concentrations were measured in the serum samples of the 4 cohorts included (HCs, early-RA, established-RA, and axSpA). Differences in adipsin concentrations between the groups were analysed using the Kruskal-Wallis test plus Dunn’s multiple comparisons test. A P value <0.05 was considered statistically significant. RA, rheumatoid arthritis; SpA, spondyloarthritis. No statistically significant differences were observed between HCs and axSpa, and between early-RA and established-RA patients. (B) Adipsin concentrations were analysed and compared by age tertiles (T1, <50 years; T2, 50–64 years; T3, ≥65 years) in established-RA patients (n=98). Differences in adipsin concentrations between the groups were analysed using the Kruskal-Wallis test plus Dunn’s multiple comparisons test. A P value <0.05 was considered statistically significant.