Table 1.
Relative effect on cardiovascular events and mortality per 1 mmol/L reduction in LDL-C
| Event | Application in model base-case | Relative risk (95% confidence interval) | Source |
|---|---|---|---|
| Major cardiovascular event | Non-coronary revascularisation | 0.78 (0.76 to 0.80) | CTT collaboration 2010 [2] |
| Any coronary revascularisation | Elective coronary revascularisation | 0.74 (0.71 to 0.79) | Weighted average using CTT collaboration 2010 [2] |
| Ischaemic stroke | Ischaemic stroke | 0.78 (0.69 to 0.80) | Weighted average using CTT collaboration 2010 [2] |
| Myocardial infarction | Myocardial infarction | 0.73 (0.67 to 0.80) | Weighted average using CTT collaboration 2010 [2] |
| Coronary heart disease death | CVD death (sensitivity analysis only) | 0.80 (0.74 to 0.87) | CTT collaboration 2010 [2] |
| All-cause mortality | All deaths | 0.90 (0.87 to 0.93) | CTT collaboration 2012 [18] |