Table 5.

Summarized results of studies on measurement properties using the EQ VAS

PROM	Reference, year	Language, country	Condition	Reliability			Hypotheses testing of construct validity
				Sample size	Study quality	Result (rating)	Sample size	Study quality	Comparator instrument: result (rating)
EQ-5D-3L Proxy-reported	Matza et al. [70]	English, United Kingdom	ADHD				83	Inadequate	ADHD-RS: Results in line with 3 hypo’s (3+)
EQ-5D-3L Proxy-reported	Matza et al. [70]	English, USA	ADHD				43	Inadequate	ADHD-RS: Results not in line with 3 hypo’s (3−)
Summary results (overall ratings)							n = 126		ADHD-RS: 3+ and 3− overall (−)
EQ-5D-3L Proxy-reported	Stolk et al. [13]	Dutch, Netherlands	Imperforate anus (1–4 years)				27	Inadequate	LSQ- 7: Results not in line with 1 hypo (1−)
EQ-5D-3L Proxy-reported	Stolk et al. [13]	Dutch, Netherlands	Imperforate anus (5–10 years)				47	Inadequate	LSQ- 7: Results not in line with 1 hypo (1−)
EQ-5D-3L Proxy-reported	Stolk et al. [13]	Dutch, Netherlands	Imperforate anus (11–15 years)				36	Inadequate	LSQ- 7: Results in line with 1 hypo (1+)
Summary results (overall ratings)							n = 110		LSQ- 7: 1+ and 2− overall (−)
EQ-5D-Y-3L Self-reported	Ravens-Sieberer et al. [14]	Italian, Italy	General population	415	Doubtful	ICC: 0.82 (+)	415	Inadequate	SRH: Results not in line with 1 hypo (1−)
EQ-5D-Y-3L Self-reported	Ravens-Sieberer et al. [14]	Spanish, Spain	General population	973	Doubtful	ICC: 0.83 (+)	973	Doubtful	KIDSCREEN- 27: Results in line with 2 hypo’s (2+) and not in line with 1 hypo (1−)
								Inadequate	SRH: Results not in line with 1 hypo (1−) Cantril-ladder: Results not in line with 1 hypo (1−)
EQ-5D-Y-3L Self-reported	Ravens-Sieberer et al. [14]	German, Germany	General population				756	Doubtful	KIDSCREEN- 27: Results in line with 3 hypo’s (3+)
								Inadequate	SRH: Results in line with 1 hypo (1+) Cantril-ladder: Results in line with 1 hypo (1+)
EQ-5D-Y-3L Self-reported	Ravens-Sieberer et al. [14]	Unclear, South Africa	General population				258	Doubtful	KIDSCREEN- 27: Results in line with 1 hypo (1+) and not in line with 2 hypo’s (2−)
								Inadequate	SRH: Results not in line with 1 hypo (1−) Cantril-ladder: Results not in line with 1 hypo (1−)
EQ-5D-Y-3L Self-reported	Ravens-Sieberer et al. [14]	Sweden, Swedish	General population				407	Doubtful	KIDSCREEN- 27: Results in line with 3 hypo’s (3+)
								Inadequate	SRH: Results not in line with 1 hypo (1−) Cantril-ladder: Results in line with 1 hypo (1+)
EQ-5D-Y-3L Self-reported	Gusi et al. [65]	Spanish, Spain	General population				477	Doubtful	KIDSCREEN- 27: Results in line with 3 hypo’s (3+)
								Inadequate	SRH: Results in line with 1 hypo (1+) Cantril-ladder: Results in line with 1 hypo (1+)
Summary results (overall ratings)				1.388		0.82 to 0.83 (+)	n = 2.871		KIDSCREEN- 27: 12+ and 3− overall (+) SRH: 2+ and 4− overall (−) Cantril-ladder: 3+ and 2− overall (−)
EQ-5D-Y-3L Proxy-reported	Gusi et al. [65]	Spanish, Spain	General population	79	Doubtful	ICC: 0.57 (−)	442	Inadequate	KIDSCREEN- 27: Results not in line with 3 hypo’s (3−) SRH: Results not in line with 1 hypo (1−) Cantril-ladder: Results in line with 1 hypo (1+)
EQ-5D-Y-3L Proxy-reported	Gusi et al. [65]	Spanish, Spain	General population	35	Doubtful	ICC: 0.66 (–)	266	Inadequate	KIDSCREEN- 27: Results in line with 1 hypo (1+) and not in line with 2 hypo’s (2−) SRH: Results not in line with 1 hypo (1−) Cantril-ladder: Results in line with 1 hypo (1+)
Summary results (overall ratings)				114		0.57 to 0.66 (–)	n = 708		KIDSCREEN- 27: 1+ and 5− (−) SRH: 0+ and 2− (−) Cantril-ladder: 2+ and 0− overall (+)

COSMIN risk of bias: very good, adequate, doubtful, or inadequate quality. Overall ratings: ‘+’ = sufficient; ‘-’ = insufficient; ‘?’ = indeterminate; ‘±’ = inconsistent. KIDSCREEN- 27: comparisons include the physical well-being, psychological well-being and KIDSCREEN- 10 index score

PROM(s) patient-reported outcome measure(s), EQ VAS visual analogue scale of the EQ-5D, n sample size, ADHD attention deficit/hyperactivity disorder, hypo(’s) hypothesis(es), ADHD-RS Attention-Deficit/Hyperactivity Disorder Rating Scale-IV—Parent Version, LSQ- 7 Langemeijer Stool Questionionaire, ICC intraclass correlation coefficient, SRH self-rated health item, Cantril-ladder Cantril’s Life-Satisfaction-Ladder