Table 1. CD, sedimentation equilibrium AUC, and SLS data for ccCor1 WT and variants.
| Peptides | [Θ]222* (103 deg·cm2·dmol-1) | Tm,† °C | MWobs/MWmonomer,‡ 50 μM/100 μM/200 μM | SLS,§ kDa |
|---|---|---|---|---|
| ccCor1 | -28.4 | 79 | 3.1/3.1/3.0 | 10.9 (3.8) |
| ccCor1-R450A | -32.2 | 67 | 3.8/3.8/4.0 | 13.8 (3.7) |
| ccCor1-R450Nle | -24.7 | 86 | 4.0/3.9/4.1 | 14.8 (3.8) |
| ccCor1-R450K | -23.0 | 66 | 3.1/3.3/3.8 | n.d. |
*
[Θ]222 measured at 5 °C at peptide concentrations (monomer) of 35 μM.
†
Tm determined at peptide concentrations (monomer) of 35 μM.
‡
Average molecular masses determined by AUC.
§
Average molecular masses determined by SLS. The molecular masses of the monomers are given in parentheses. n.d., not determined.