Time evolution of the involved species in model 1, illustrating the consequence of mirror-symmetry breaking in a typical simulation starting from achiral conditions and by using an appropriate set of parameters: [A]0 = 1 M, [R]0 = [S]0 = 0, k0 = 10–6 s–1, k1 = 1 M–1·s–1, and k2 = 100 M–1·s–1.