Table 1:
Simulated trial of complete information
Patient | Latent | Pr (C-DLT) at | Latent | Pr (P-DLT) at | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Number | C-DLT | dose level | P-DLT | dose level | ||||||||
0.05 | 0.05 | 0.25 | 0.40 | 0.55 | 0.17 | 0.18 | 0.35 | 0.50 | 0.65 | |||
1 | 0.04 | 1 | 1 | 1 | 1 | 1 | 0.85 | 0 | 0 | 0 | 0 | 0 |
2 | 0.98 | 0 | 0 | 0 | 0 | 0 | 0.46 | 0 | 0 | 0 | 1 | 1 |
3 | 0.31 | 0 | 0 | 0 | 1 | 1 | 0.37 | 0 | 0 | 0 | 1 | 1 |
4 | 0.71 | 0 | 0 | 0 | 0 | 0 | 0.41 | 0 | 0 | 0 | 1 | 1 |
5 | 0.43 | 0 | 0 | 0 | 0 | 1 | 0.19 | 0 | 0 | 1 | 1 | 1 |
6 | 0.24 | 0 | 0 | 1 | 1 | 1 | 0.56 | 0 | 0 | 0 | 0 | 1 |
7 | 0.47 | 0 | 0 | 0 | 0 | 1 | 0.27 | 0 | 0 | 1 | 1 | 1 |
8 | 0.54 | 0 | 0 | 0 | 0 | 1 | 0.13 | 1 | 1 | 1 | 1 | 1 |
9 | 0.48 | 0 | 0 | 0 | 0 | 1 | 0.91 | 0 | 0 | 0 | 0 | 0 |
10 | 0.28 | 0 | 0 | 0 | 1 | 1 | 0.71 | 0 | 0 | 0 | 0 | 0 |
11 | 0.76 | 0 | 0 | 0 | 0 | 0 | 0.67 | 0 | 0 | 0 | 0 | 0 |
12 | 0.14 | 0 | 0 | 1 | 1 | 1 | 0.36 | 0 | 0 | 0 | 1 | 1 |
13 | 0.97 | 0 | 0 | 0 | 0 | 0 | 0.45 | 0 | 0 | 0 | 1 | 1 |
14 | 0.60 | 0 | 0 | 0 | 0 | 0 | 0.70 | 0 | 0 | 0 | 0 | 0 |
15 | 0.06 | 0 | 0 | 1 | 1 | 1 | 0.89 | 0 | 0 | 0 | 0 | 0 |
16 | 0.13 | 0 | 0 | 1 | 1 | 1 | 0.48 | 0 | 0 | 0 | 1 | 1 |
17 | 0.97 | 0 | 0 | 0 | 0 | 0 | 0.21 | 0 | 0 | 1 | 1 | 1 |
18 | 0.46 | 0 | 0 | 0 | 0 | 1 | 0.49 | 0 | 0 | 0 | 1 | 1 |
0.06 | 0.06 | 0.28 | 0.39 | 0.67 | 0.06 | 0.06 | 0.22 | 0.61 | 0.67 |