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DNA region containing the direct repeats of whole pCoo and repeats after resolution of the pCoo cointegrate. The repeats (arrows) in whole pCoo are labeled DRI and DRII. The repeat regions contained within the products of recombination are labeled pCoo R64 DR and pCoo R100 DR. The start sites and directions of primers 1, 2, 3, and 4 which flank the repeated region are indicated by small arrows. See Table S2 in the supplemental material for primer sequences.
