The extracytoplasmic stress response regulons are strongly induced in the absence of CRP. degP cyaA crp mutant derivative strains were grown in LB broth at 41°C, and the amount of β-galactosidase activity was assayed. The levels of β-galactosidase generated in strains TS2A (cyaA+; white bar), TS18A (cyaAΔ11; light gray bar), TS15A (cyaA::Tn5; horizontally striped bar), TS16A (cyaA1400::kan; dark gray bar), TS2AB (cyaA+ crp::cam; white vertically striped bar), TS18AB (cyaAΔ11 crp::cam; light gray vertically striped bar), TS15AB (cyaA::Tn5 crp::cam; cross-hatched bar), and TS16AB (cyaA1400::kan crp::cam; dark gray vertically striped bar) are shown.