Table 2.
Associations between dietary patterns and intake of methyl-donor nutrients and DNA methylation of circadian genes, all participants.
| Probe | Chr | Position | Relation to island | Strand | UCSC gene category | Gene | Beta | SE | p–value | q–value |
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| Meat & starchy foods | ||||||||||
| cg19170589 | chr15 | 60883569 | Island | + | Body | RORA | 5.34 × 10−3 | 1.44 × 10−3 | 2.33 × 104 | 0.159 |
| cg15048607 | chr4 | 56310021 | OpenSea | + | Body | CLOCK | −6.46 × 10−3 | 1.83 × 10−3 | 4.50 × 104 | 0.159 |
| Riboflavin | ||||||||||
| cg06337557 | chr11 | 92702373 | N_Shore | − | TSS1500 | MTNR1B | −1.50 × 10−2 | 4.17 × 10−3 | 3.41 × 104 | 0.162 |
| cg02076826 | chr15 | 61477299 | OpenSea | − | Body | RORA | −6.53 × 10−3 | 1.85 × 10−3 | 4.58 × 104 | 0.162 |
| Vitamin B6 | ||||||||||
| cg09615953 | chr1 | 7886633 | N_Shore | + | Body | PER3 | 3.73 × 10−3 | 1.07 × 10−3 | 5.09 × 104 | 0.180 |
| cg06337557 | chr11 | 92702373 | N_Shore | − | TSS1500 | MTNR1B | −1.31 × 10−2 | 3.68 × 10−3 | 4.03 × 104 | 0.180 |
Chr, chromosome; SE, standard error.
Table only showed significantly associated CpG sites at q ≤ 0.20.
Models adjusted for age, sex, ever smoking, maternal education, batch effects, % granulocytes, monocytes, natural killer cells, CD8 T cells, and CD4 T cells.