Table 1.

Diagnostic criteria for Crohn’s disease recommended by the World Health Organization.

Items	Clinical manifestation	Radiological imaging	Endoscopy	Biopsy	Surgical specimen
① Discontinuous or segmental changes	‐	+	+	‐	+
② Cobblestone-like appearance or longitudinal ulcers	‐	+	+	‐	+
③ Whole-wall inflammatory response changes	+	+	‐	+	+
④ Non-caseous granulomas	‐	‐	‐	+	+
⑤ Fissures, fistulas	+	+	‐	‐	+
⑥ Perianal lesions	+	‐	‐	‐	‐

Patients with ①, ②, ③ are suspected; add ④, ⑤, ⑥ one of the 3 can be diagnosed; you can also be diagnosed with ④, as long as you add ①, ②, ③ 2 of the 3. “‐” means that there is no such manifestation, “+” means that there is such manifestation.