Table 2.
Laboratory tests before KTx in patients with and without PTDM.
| Variable | No PTDM group n = 102 |
PTDM group n = 28 |
Total n = 130 |
P value |
|---|---|---|---|---|
| HbA1c %, median (IQR) | 5.300 (5, 5.500) | 5.55 (5.175, 5.8) | 5.3 (5, 5.6) | .022 |
| HbA1c > 5.7%, n (%) | 8 (7.84) | 8 (28.57) | 16 (12.31) | .007 |
| HbA1c IFCC mmol/mol median (IQR) |
34 (31, 36) | 37 (33, 39) | 35 (31, 37) | .017 |
| HbA1c IFCC > 39 mmol/mol, n (%) | 8 (7.84) | 8 (28.57) | 14 (10.77) | .007 |
| Glucose mg/dL, median (IQR) | 84 (78.5, 93) | 89 (83.75, 98.5) | 86 (79, 95) | .021 |
| Glucose above 99 mg/dL, n (%) | 8 (7.8) | 7 (25) | 15 (11.5) | .017 |
| Insulin µU/mL, median (IQR) | 6.7 (5.075, 9.2) | 7.7 (5.7, 11.2) | 6.9 (5.1, 10.1) | .37 |
| QUICKY, median (IQR) | 0.351 (0.33, 0.37) | 0.36 (0.345, 0.381) | 0.36 (0.34, 0.38) | .06 |
| QUICKY < 0.34, n (%) | 14 (15.2%) | 8 (29.6%) | 22 (18.5%) | .096 |
| HOMA-IR, median (IQR) | 1.413 (1.046, 2.0310 | 1.730 (1.284, 2.535) | 1.44 (1.07, 2.17) | .309 |
| HOMA-IR > 2, n (%) | 23 (25) | 10 (37) | 33 (27.7) | .223 |
| TyG index, median (IQR) | 8.677 (8.446, 9.061) | 8.675 (8.355, 8.934) | 8.675 (98.372, 8.942) | .384 |
| C-peptide before KTx (ng/mL), median (IQR) | 5.9 (4.235, 9.4) | 7.315 (6.035, 9.06) | 6.695 (4.48, 9.38) | .06 |
| Albumin before KTx (g/L) median (IQR) |
39 (37, 41) | 39 (37, 40) | 3.9 (3.7, 4.1) | .56 |
| Homocystein µmol/L, median (IQR) |
22.2 (16.9, 31.7) | 22.9 (18.575, 28.657) | 22 (17.1, 31.4) | .847 |
| Homocystein > 15 µmol/L | 79 (77.5) | 24 (85.7%) | 103 (79.2) | .344 |
| Cholesterol mg/dL, median (IQR) |
198 (162.5, 229) | 189 (160, 231.25) | 197 (162, 229.00) | .647 |
| TG mg/dL, median (IQR) | 138 (100, 174.5) | 133 (104.5, 174) | 138 (100, 176) | .414 |
| HDL mg/dL, median (IQR) | 45 (38, 55) | 47 (39, 56) | 45.5 (38, 56) | .992 |
| LDL mg/dL, median (IQR) | 121.7 (92.1, 152.95) | 104.7 (89, 142.5) | 120 (91, 153) | .608 |
| Uric acid mg/dL, median (IQR) | 4.8 (3.7, 6.2) | 4.2 (3.2, 5.3) | 4.7 (3.5, 6.15) | .38 |
HOMA-IR = HOmeostatic Model Assesment-Insulin Resistance, HOMA-IR = fasting insulin [mU/mL] × fasting glucose [mg/dL]/405.
QUICKI (Quantitative Insulin Sensitivity Check Index) = 1/log fasting insulin [µU/mL] × log fasting glucose [mg/dL].
TyG index = ln [fasting triglycerides (mg/dL) × fasting glucose (mg/dL)/2].
HBA1c = glycosylated hemoglobin, Type A1c; HDL = high-density lipoprotein; HOMA-IR Index = homeostatic model assessment of insulin resistance index; KTx = kidney transplantation; N = number of patients; OR = odds ratio; QUICKI = quantitative insulin-sensitivity check index; TyG index = triglycerides and glucose index.