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. 2025 Aug 15;104(33):e43931. doi: 10.1097/MD.0000000000043931

Table 5.

Baseline characteristics and treatment effects between Group 2 and VIBRANT 52weeks trial.

Group 3
(first Bevacizumab and then Aflibercept or all Aflibercept)
n = 15
VIBRANT 52weeks trial
N = 91
Average amount of IVI 3.73 (1.58) 9.0 (1.8) P < .0001*
Portion of patients with improvement < 15ETDRS letters(%) 2 (13.33%) 32 (35.16%) P = .22
Portion of patients with improvement ≧ 15 ETDRS letters(%) 12 (80%) 52 (57.14%)
Portion of patients with ETDRS letters loss(%) 1 (6.67%) 7 (7.7%)
Average initial CRT,
μm, mean(SD)
516.33 (130.41)
Average CRT improvement, μm, mean(SD) 237.67 (135.46) 283.9 (–)
*

Two sample t test.

Fisher exact test.

Not available data for further calculation.

CRT = central retinal thickness, IVI = intravitreal injection, SD = standard deviations.