Table 5.
Baseline characteristics and treatment effects between Group 2 and VIBRANT 52weeks trial.
| Group 3 (first Bevacizumab and then Aflibercept or all Aflibercept) n = 15 |
VIBRANT 52weeks trial N = 91 |
||
|---|---|---|---|
| Average amount of IVI | 3.73 (1.58) | 9.0 (1.8) | P < .0001* |
| Portion of patients with improvement < 15ETDRS letters(%) | 2 (13.33%) | 32 (35.16%) | P = .22† |
| Portion of patients with improvement ≧ 15 ETDRS letters(%) | 12 (80%) | 52 (57.14%) | |
| Portion of patients with ETDRS letters loss(%) | 1 (6.67%) | 7 (7.7%) | |
| Average initial CRT, μm, mean(SD) |
516.33 (130.41) | –‡ | –‡ |
| Average CRT improvement, μm, mean(SD) | 237.67 (135.46) | 283.9 (–)‡ | –‡ |
Two sample t test.
Fisher exact test.
Not available data for further calculation.
CRT = central retinal thickness, IVI = intravitreal injection, SD = standard deviations.