Table 5.

Correlation between serum biomarkers and CT-ECV (Spearman analysis).

Serum biomarker	Correlation coefficient (ρ)	P-value	Strength of association
CEA	0.42	<.001	Moderate
CA19-9	0.38	<.001	Weak–moderate
CA125	0.51	<.001	Moderate
NLR	0.47	<.001	Moderate
PLR	0.39	<.001	Weak–moderate
LMR	−0.36	<.001	Weak–moderate

CA125 = carbohydrate antigen 125, CA19-9 = carbohydrate antigen 19-9, CEA = carcinoembryonic antigen, CT-ECV = computed tomography-derived extracellular volume fraction, LMR = lymphocyte-to-monocyte ratio, NLR = neutrophil-to-lymphocyte ratio, PLR = platelet-to-lymphocyte ratio.

^*Strength of association criteria: ρ <0.3 (weak), 0.3≤ ρ <0.6 (moderate), ρ ≥0.6 (strong).