Table 1.

Forced normalization diagnostic criteria.

Primary (essential) criteria
1.  Established diagnosis of epilepsy based on clinical history, EEG, an imaging 2.  Presence of a behavioral disturbance of acute/subacute onset characterized by 1 or more of the following:    Psychosis with thought disorder, delusions, hallucinations    Significant mood change, hypomania, mania or depression    Anxiety with depersonalization, derealization 3A. Reduction in the total number of spikes counted in 60 min awake EEG recording with a 16-channel machine, using standard 10 to 20 electrode placement, by over 50% compared to a similar recording performed during a normal state of behavior. 3B. Report of complete cessation of seizures for a least 1 wk corroborated any relative or caregivers.
Supportive criteria
Recent change (within 30 d) of pharmacotherapeutic regimen Report of similar episodes of seizure cessation and behavioral disturbance in the past, from close relative or caregivers, or general practitioner, or documentation of this in hospital records with or without EEG evidence. This may or may not be linked with and anticonvulsant drug
To make the diagnosis
Primary criteria 1, 2 and 3A OR Primary criteria 1, 2 and 3B and 1 supportive criterion

EEG = electroencephalogram.