Table 3.
Results of heterogeneity by the Cochran Q test and the MR-PRESSO global test.
| Exposure/Outcome | Pleio P value | Intercept | Cochran Q | df | Heterogeneity P value | MR-PRESSO | |
|---|---|---|---|---|---|---|---|
| RSSobs | P value | ||||||
| COPD/BE | .06 | 0.021 | 11.948 | .6 | |||
| MR Egger | 32.228 | 26 | .186 | ||||
| IVW | 37.013 | 27 | .095 | ||||
| BE/COPD | .952 | 0.0007 | 9.96 | .685 | |||
| MR Egger | 63.653 | 49 | .078 | ||||
| IVW | 63.658 | 50 | .093 | ||||
BE = Barrett’s esophagus, COPD = chronic obstructive pulmonary disease, IVW = inverse variance weighted, MR = Mendelian randomization, MR-PRESSO = Mendelian Randomization Pleiotropy RESidual Sum and Outlier.
Statistical significance is expressed directly by the P-value (P < .05).