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. 2025 Aug 21;16:1590. doi: 10.1007/s12672-025-03393-3

Fig. 4.

Fig. 4

METTL3_14 regulated AS of pancreatic cancer related genes by binding directly to RNA. (A) Venn diagram showing the overlap of Fig. 3 overlap peaks and METTL3_14-regulated alternative splicing events (use non-IR region). (B) Bar plot exhibited the most enriched GO biological process results of genes which the overlap peaks (showed in A) located (use Symbol). (C) Venn diagram showing the overlap of Fig. 3 overlap peaks and METTL3_14-regulated NIR RASG (use Region). (D) Bar plot exhibited the most enriched GO biological process results of the overlapped genes in C. (E) IGV-sashimi plot showed the METTL3_14-regulated alternative splicing events across mRNA of EIF4A2. The transcript of the gene was plotted at the bottom of the graph