Table 5.
Genetic interaction between mutations affecting damage-sensing functions and signal-transduction cascade components: Rearrangement breakpoint analysis
| Relevant genotype | Strain | Telomere addition | Translocation, non,micro |
|---|---|---|---|
| Wild type* | 3615 | 5 | 1,0 |
| mec1Δ sml1Δ* | 3735 | 9 | 0,0 |
| tel1Δ* | 3731 | 0 | 0,6 |
| tel1Δ rfc5-1* | 3775 | 2 | 4,4 |
| tel1Δ sgs1Δ | 4566 | 0 | 4,6 |
| tel1Δ rad9Δ | 4505 | 7 | 1,4 |
| tel1Δ mec3Δ* | 3773 | 4 | 1,4 |
| mec1Δ sml1Δ rad9Δ | 4527 | 9 | 0,2 |
The numbers reported are the actual numbers of each type of event seen. The designation n,n indicates the number of nonhomology breakpoints observed followed by the number of microhomology breakpoints observed.
*
Data from Myung et al. (22).