. 2002 Mar 26;99(7):4500–4507. doi: 10.1073/pnas.062702199

Table 6.

Genetic interaction between mutations affecting damage-sensing and telomere-maintenance functions

Relevant genotype	Wild type		est2Δ		pif1-m2
Relevant genotype	Strain	GCR rate × 10¹⁰	Strain	GCR rate × 10¹⁰	Strain	GCR rate × 10¹⁰
Wild type	3615	3.5 (1)^*	4347	1.2 (0.3)^†	4343	830 (237)^†
rad9Δ	3719	20 (6)^*	4511	4.5 (1.3)	4533	1,310 (374)
rad17Δ	3721	30 (9)^*	4513	6.0 (1.7)	4535	1,150 (329)
rad24Δ	3723	40 (11)^*	4515	8.5 (2.4)	4611	1,760 (503)
mec3Δ	3725	190 (54)^*	4517	50 (14)	4405	3,100 (886)
rfc5-1	3727	660 (189)^*	4413	440 (125)^†	4403	13,300 (3,800)^†
sgs1Δ	3813	77 (22)	4583	7.3 (2)	4567	2,900 (829)
mec1Δ sml1Δ	3735	680 (194)^*	4415	280 (80)^*	4407	18,000 (5,200)

( ) indicates the GCR rate relative to the wild-type GCR rate. Note that the wild-type GCR rate is 3.5 × 10⁻¹⁰.

Data from Myung et al. (22).

^†

Data from Myung et al. (61).