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. 2002 Mar 19;99(7):4574–4579. doi: 10.1073/pnas.062037499

Figure 2.

Figure 2

Effect of dexamethasone on trabecular bone volume fraction (TB/TV) and trabecular thickness (Tb.Th) within 4 weeks of treatment, measured by μ-MRI (open circle, control; filled circle, treated). (a) TB/TV. (b) Tb.Th. (c) Same as a for whole-body BMD obtained by DEXA (open circle, control; filled circle, treated). (d) Longitudinal images of the distal femur obtained by reformation of transverse MR images, with epiphyseal growth plate appearing as a dark band separating epiphysis and metaphysis, showing marked atrophy of epiphyseal growth plate thickness on MR reconstructed images in the treated animal. (e) Change in epiphyseal growth plate thickness (open circle, control; filled circle, treated). All data are expressed as percentage changes relative to baseline in each group (mean ± SD). *, P < 0.05; **, P < 0.01; ***, P < 0.005; and ****, P < 0.0001, treated compared with control, Student's unpaired, two-tailed t test.