Table 1.
Cytogenetic data.
| Mouse number | Biopsy site | Passage number | Ploidy < 2n | Ploidy = 2n | Ploidy 2n-4n | Ploidy = 4n | Ploidy > 4n | Total number of cells analyzed | Polyploid cells (%)a |
| Wild-type week 6 | |||||||||
| 30 | AM | 1 | 1 | 29 | 1 | 11 | 10 | 52 | 19 |
| 31 | PF | 1 | 2 | 46 | 0 | 11 | 0 | 59 | 0 |
| 31 | AM | 1 | 1 | 26 | 0 | 19 | 4 | 50 | 8.0 |
| 31 | AM | 4 | 0 | 3 | 0 | 3 | 5 | 11 | 45 |
| Wild-type week 12 | |||||||||
| 76 | EL | 1 | 2 | 46 | 0 | 4 | 0 | 52 | 0 |
| 76 | EL | 5 | 0 | 50 | 0 | 17 | 0 | 67 | 0 |
| 76 | PF | 1 | 0 | 42 | 0 | 7 | 1 | 50 | 2.0 |
| 76 | AM | 1 | 0 | 10 | 0 | 1 | 1 | 12 | 8.3 |
| 77 | EL | 1 | 0 | 60 | 0 | 4 | 0 | 64 | 0 |
| 77 | EL | 5 | 0 | 22 | 3 | 20 | 5 | 50 | 10 |
| 77 | EL | 1 | 0 | 46 | 0 | 5 | 1 | 52 | 19 |
| 77 | AM | 1 | 0 | 85 | 0 | 30 | 2 | 117 | 1.7 |
| R6/2 week 6 | |||||||||
| 38 | PF | 1 | 0 | 45 | 0 | 5 | 0 | 50 | 0 |
| 38 | AM | 1 | 0 | 39 | 0 | 12 | 5 | 56 | 8.9 |
| 38 | AM | 4 | 0 | 32 | 0 | 32 | 1 | 65 | 1.5 |
| 38 | LC | 1 | 0 | 24 | 2 | 17 | 7 | 50 | 14 |
| 39 | AM | 1 | 0 | 33 | 1 | 12 | 4 | 50 | 8.0 |
| 39 | AM | 4 | 0 | 25 | 0 | 30 | 3 | 58 | 5.2 |
| R6/2 week 12 | |||||||||
| 78 | EL | 1 | 1 | 50 | 0 | 4 | 0 | 55 | 0 |
| 78 | EL | 5 | 0 | 39 | 1 | 19 | 3 | 62 | 4.8 |
| 78 | PF | 1 | 0 | 53 | 0 | 3 | 0 | 56 | 0 |
| 78 | AM | 1 | 0 | 30 | 0 | 4 | 1 | 35 | 2.9 |
| 79 | PF | 1 | 0 | 70 | 1 | 7 | 0 | 78 | 0 |
| 79 | AM | 1 | 0 | 50 | 1 | 7 | 0 | 58 | 0 |
a Cells with a ploidy level above the tetraploid (4n). AM, abdominal muscle cells; PF, peritoneal fat fibroblasts; EL, ear lobe fibroblasts; LC, liver cells.