Membrane reactor |
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Advantages |
High productivities, high cell concentration can be achieved inside the reactor, clear permeates for further separation |
Disadvantages |
Fouling with cells, cost prohibits their use in low cost large volume chemical production |
Immobilized cell reactors |
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Covalent bond formation
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Advantages |
High cell concentration may be achieved, high productivity |
Disadvantages |
Cell growth inside matrix may be restricted, cells leach out of the matrix and hence centrifugation of effluent may be required, chemical may affect the cells |
Entrapment
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Advantages |
High cell concentration may be achieved, high productivity |
Disadvantages |
Matrix often starts disintegration with time, cells leach out of matrix, centrifugation of reactor effluents is required for further separation |
Biofilm
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Advantages |
Comparatively high reactor productivities and high cell concentrations are achieved, reactors run longer and are economic to operate |
Disadvantages |
Effluent centrifugation is required |