Table 2.
Preferential conservation of uAUGs in mouse and rat orthologous 5′-UTRs
Trinucleotide | Triplet present in mouse but not in rat (%) | Triplet conserved in mouse and rat (%) | Triplet present in rat but not in mouse (%) |
---|---|---|---|
AUG | 9 | 81 | 10 |
AGU | 17 | 65 | 18 |
GUA | 20 | 57 | 23 |
GAU | 15 | 69 | 16 |
UAG | 18 | 62 | 20 |
UGA | 13 | 72 | 15 |
Fishers's exact test: 1539 conserved uAUGs, 359 non-conserved uAUGs, 11 218 conserved AGU/GUA/GAU/UAG/UGAs, 5703 non-conserved AGU/GUA/GAU/UAG/UGAs and P = 2.9 × 10−42.