Table 3.
Preferential conservation of uAUGs in human–mouse stop-codon-bounded 5′-UTR alignments (5′-UTR<stop set)
Trinucleotide | Triplet present in human, but not in mouse (%) | Triplet conserved in human and mouse (%) | Triplet present in mouse, but not in human (%) |
---|---|---|---|
AUG | 9 | 84 | 7 |
AGU | 17 | 69 | 14 |
GUA | 20 | 62 | 18 |
GAU | 17 | 70 | 13 |
UAG | 15 | 70 | 15 |
UGA | 16 | 72 | 12 |
Fishers's exact test: 255 conserved uAUGs, 49 non-conserved uAUGs, 1124 conserved AGU/GUA/GAU/UAG/UGAs, 491 non-conserved AGU/GUA/GAU/UAG/UGAs and P = 1.52 × 10−7.