Table 8.
Expected and observed numbers of uAUG triplets and shuffled triplets per 1000 nt in mammalian and yeast 5′-UTRs
| Species, triplets | Expected | Observed |
|---|---|---|
| Human uAUGs Human | 12.6 | 7.4 |
| AGU/GUA/GAU/UAG/UGAs | 63.0 | 47.7 |
| Mouse uAUGs | 12.6 | 6.9 |
| Mouse AGU/GUA/GAU/UAG/UGAs | 63.0 | 48.2 |
| Rat uAUGs | 12.7 | 7.6 |
| Rat AGU/GUA/GAU/UAG/UGAs | 63.5 | 49.4 |
| Yeast uAUGs | 17.7 | 10.6 |
| Yeast AGU/GUA/GAU/UAG/UGAs | 88.5 | 73.6 |
The statistical significance of the differences between expected and observed frequencies of uAUG and shuffled triplets were estimated using the χ2 test (2 × 2 tables). In all cases, the difference for uAUGs was significantly greater than that for the combined shuffled triplets (P < 0.001).