Table 3.
Race-stratified Lp(a)-related risk of prevalent CAVD.a
| Lp(a)-M (mg/dL) | Lp(a)-C (mg/dL) | Lp(a)-P (nmol/L) | |
|---|---|---|---|
| Black | |||
| Upper 15th% cutoff value | 83.9 | 9.9 | 167 |
| Estimated RR | 1.50 | 1.50 | 1.36 |
| 95% CI | (1.02–2.21) | (1.02–2.21) | (0.95–1.96) |
| P value | 0.04 | 0.04 | 0.10 |
| White | |||
| Upper 15th% cutoff value | 49.3 | 5.7 | 102 |
| Estimated RR | 1.71 | 1.74 | 1.74 |
| 95% CI | (1.37–2.14) | (1.37–2.21) | (1.37–2.20) |
| P value | <0.0001 | <0.0001 | <0.0001 |
| Chinese-American | |||
| Upper 15th% cutoff value | 36.2 | 3.0 | 62 |
| Estimated RR | 1.847 | 1.949 | 1.725 |
| 95% CI | (0.45–7.53) | (0.72–5.29) | (0.40–7.54) |
| P value | 0.39 | 0.19 | 0.47 |
| Hispanic | |||
| Upper 15th% cutoff value | 46.0 | 4.6 | 93 |
| Estimated RR | 1.26 | 1.50 | 1.50 |
| 95% CI | (0.84–1.88) | (1.07–2.11) | (1.06–2.12) |
| P value | 0.26 | 0.02 | 0.02 |
The P values are in bold to highlight the significance.
a
Relative risk ratios (RR) and 95% CI are presented for individuals in respective upper 15th percentiles for each Lp(a) marker. Adjustments were made for age, sex, hypertension, smoking, education status, diabetes, LDL-C, and HDL-C. Upper 15th percentile cutoff values are shown for each analyte and racial/ethnic group.